2026
Untangling mechanisms for cerebellar neural specification using human pluripotent stem cell-derived organoids
Helgueta S, Bonafina A, Olivié N, Coumans B, Nguyen L, Espuny-Camacho I. bioRxiv. Preprint. doi:10.64898/2026.04.27.720597. Senior author.
2025
SARS-CoV-2 infection triggers inflammatory conditions and astrogliosis-related gene expression in long-term human cortical organoids
Colinet M, et al. Stem Cells. Senior author.
Ccp1 depletion disrupts network integration of hippocampal parvalbumin interneurons
Le Bail R, et al. iScience.
2024
Huntington’s disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids
Galimberti M, et al. Nature Communications.
2022
Brain regional identity and cell type specificity landscape of human cortical organoid models
Magni M, et al. International Journal of Molecular Sciences. Senior author.
2021
The coding and long noncoding single-cell atlas of the developing human fetal striatum
Bocchi VD, et al. Science.
Learning about cell lineage, cellular diversity and evolution of the human brain through stem cell models
Le Bail R, et al. Current Opinion in Neurobiology. Senior author.
2018
Human pluripotent stem-cell-derived cortical neurons integrate functionally into the lesioned adult murine visual cortex in an area-specific way
Espuny-Camacho I, et al. Cell Reports. First author.
2017
Hallmarks of Alzheimer’s disease in stem-cell-derived human neurons transplanted into mouse brain
Espuny-Camacho I, et al. Neuron. First author.
2016
Altered neuronal network and rescue in a human MECP2 duplication model
Nageshappa S, et al. Molecular Psychiatry.
2015
Area-specific reestablishment of damaged circuits in the adult cerebral cortex by cortical neurons derived from mouse embryonic stem cells
Michelsen KA, et al. Neuron.
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia
Raitano S, et al. Stem Cell Reports.
2014
Thinking out of the dish: what to learn about cortical development using pluripotent stem cells
van den Ameele J, et al. Trends in Neurosciences. Senior author.
2013
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo
Espuny-Camacho I, et al. Neuron. First author.
2010
Peroxisome proliferator-activated receptor gamma enhances the activity of an insulin degrading enzyme-like metalloprotease for amyloid-β clearance
Espuny-Camacho I, et al. Journal of Alzheimer’s Disease. First author.
2008
An intrinsic mechanism of corticogenesis from embryonic stem cells
Gaspard N, et al. Nature.
2005
Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice
Dominguez D, Tournoy J, Hartmann D, Huth T, Cryns K, Deforce S, Serneels L, Espuny-Camacho I, et al. Journal of Biological Chemistry 280(35):30797–30806.
2004
Peroxisome proliferator-activated receptor γ induces a clearance mechanism for the amyloid-β peptide
Espuny Camacho I, Serneels L, Spittaels K, Merchiers P, Dominguez D, De Strooper B. Journal of Neuroscience 24(48):10908–10917. First author.